Artificial oocyte activation: physiological, pathophysiological and ethical aspects

Physiological and pathophysiological aspects of ceramide.

Activation of cells by receptor- and nonreceptor-mediated stimuli not only requires a change in the activity of signaling proteins but also requires a reorganization of the topology of the signalosom in the cell. The cell membrane contains distinct domains, rafts that serve the spatial organization of signaling molecules in the cell. Many receptors or stress stimuli transform rafts by the gener...

Physiological and pathophysiological aspects in Herophilos writings

Invited Review Physiological and pathophysiological aspects of ceramide

Gulbins, Erich, and Pin Lan Li. Physiological and pathophysiological aspects of ceramide. Am J Physiol Regul Integr Comp Physiol 290: R11–R26, 2006; doi:10.1152/ajpregu.00416.2005.—Activation of cells by receptorand nonreceptor-mediated stimuli not only requires a change in the activity of signaling proteins but also requires a reorganization of the topology of the signalosom in the cell. The c...

Biological, physiological, pathophysiological, and pharmacological aspects of ghrelin.

Ghrelin is a peptide predominantly produced by the stomach. Ghrelin displays strong GH-releasing activity. This activity is mediated by the activation of the so-called GH secretagogue receptor type 1a. This receptor had been shown to be specific for a family of synthetic, peptidyl and nonpeptidyl GH secretagogues. Apart from a potent GH-releasing action, ghrelin has other activities including s...

ESPEN guideline on ethical aspects of artificial nutrition and hydration.

BACKGROUND The worldwide debate over the use of artificial nutrition and hydration remains controversial although the scientific and medical facts are unequivocal. Artificial nutrition and hydration are a medical intervention, requiring an indication, a therapeutic goal and the will (consent) of the competent patient. METHODS The guideline was developed by an international multidisciplinary w...